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Depression

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People sometimes say they feel ‘depressed’. What they generally mean is that at the time they are feeling ‘down’ or ‘blue’. These short lived feelings are quite normal with everyone experiencing them from time to time. ‘True’ depression, however, is quite different. It is characterised by a depressed mood for a period of two weeks or more and can include a number of other symptoms (see Symptoms). People with depression often have an imbalance of particular brain chemicals (eg., serotonin) in the brain. Depression is classified according to its severity; mild, moderate or severe. This factsheet does not cover depression associated with bi-polar disorder as this is a distinct condition. For information on bi-polar disorder contact beyondblue (see Other contacts).

Depression is a very common condition and can affect people of all ages. Up to one in six men and up to one in four women will experience depression at some time during their life (1). From puberty onwards, women are twice as likely as men to be affected (2).

It is quite common for a person with depression to also have an anxiety disorder. Frequently, the anxiety disorder precedes the depression. Having an anxiety disorder increases the chances of longer and more frequent bouts of depression (3). For more information on anxiety disorders see our factsheet (available on our website or by phoning Women’s Health).

Unfortunately, about half of those with depression will not visit a health professional (4). While depression can be a serious condition, help is available. There are a number of effective treatments for depression. Seeking professional help early can help people recover more quickly.

Symptoms

In addition to depressed mood, symptoms may include:

  • Loss of pleasure or interest in most activities
  • Changes in appetite (increase or decrease)
  • Changes in weight (increase or decrease)
  • Changes in sleeping patterns (sleeping too much, insomnia, early morning awakening)
  • Decreased energy, fatigue
  • Feeling worthless or guilty
  • Difficulty concentrating or thinking, indecisiveness
  • Irritability
  • Loss of sexual interest
  • Recurrent thoughts of death or suicide.

These symptoms will vary in severity from person to person. The symptoms of someone with mild depression will still allow them to function, although perhaps not as adequately as before. Conversely, severe depression will significantly disrupt the person’s work, social and domestic activities and there may be a risk of suicide. If a person is having suicidal thoughts or if friends and family are worried their loved one is suicidal they should contact Lifeline on 13 11 44.

Causes

A person’s depression is generally due to a combination of factors:

Social-cultural

  • Relationship breakdown/difficulties
  • Being socially disadvantaged (poverty, unemployed)
  • Stressful life events (loss of a loved one, illness in family, family separation, trauma)
  • Adjustment to a life transition (marriage, parenthood, menopause, retirement)
  • Lack of stimulating activities in one’s life
  • Caring for someone with a chronic physical or mental disorder
  • Physical or sexual abuse as a child or adult
  • Being in residential care (elderly/disabled)
  • Loneliness and/or isolation
  • Racism
  • Exploring, questioning or identifying as lesbian, gay, bisexual and/or transgender
  • Having a parent with a mental illness* (5,6).

Biological and psychological

  • Negative thought patterns (ie., pessimistic, worrier)
  • Avoidant coping style (using strategies to avoid directly addressing the stressful event)
  • Having an anxiety disorder
  • Having a chronic illness
  • Family history of mental illness*

* People can inherent a tendency to get depression. It is thought that as much as 40% of major depression cases are due to genetics. In addition, it is also believed that ways of thinking and coping strategies associated with depression can be learnt within families.

Depression can also be the result of particular medications or an underlying medical condition (eg., low thyroid function, stroke, Parkinson’s disease, dementia) (7).

Diagnosis

The most important step in addressing depression is recognising that it is an illness requiring treatment. It is important that people receive an accurate assessment and diagnosis as this will ensure they receive the appropriate treatment.

People are often confused by the range of health professionals working in the area of mental health and are unsure of the differences between them. A good place to start is to visit a general practitioner (GP). They can provide the person and their family with information on depression so they have a better understanding of the condition. Some GPs also provide psychological therapies. If necessary, a GP will refer the person to other relevant health professionals who treat depression, including a:

  • Psychiatrist - a medical specialist who has undertaken higher training in the field of psychiatry. A psychiatrist may offer psychological therapies and physical treatments (medications). They are experts on the most appropriate medications to take.
  • Clinical psychologist - completed a degree in the field of psychology as well as a number of years under the professional supervision of another registered psychologist. They are not a medical doctor and, therefore, cannot prescribe medications. A clinical psychologist provides psychological therapies.
  • Counsellor - can have a variety of training from postgraduate qualifications to a certificate course. At present, there are no minimum training standards for people using the title counsellor. A counsellor provides psychological therapies.

Finding a health professional that one feels comfortable with and confident in is important. Different health professionals and treatment styles will suit different people. It is often a good idea to meet with a health professional for an introductory session. This will provide an opportunity to ask about their qualifications and experience, their methods, fees and to get a general feeling about their attitude and approach.

People may find it helpful to choose a health professional that belongs to a professional body such as the Royal Australian and New Zealand College of Psychiatrists (RANZCP), Australian Psychological Society (APS) or the Australian Counselling Association (ACA).

Medicare rebates are available for some health professional visits related to the diagnosis and treatment of depression. People can ask their GP about the Medicare rebates or contact Medicare Australia on 13 20 11.

Treatment

The treatment required depends on the severity of a person’s depression. For example, someone with mild depression may find relief from self-help strategies and/or complementary medicines while a person with moderate or severe depression may require a combination of psychological therapies and medication.

Psychological therapies
Psychological therapies are provided by a variety of health professionals including psychiatrists, psychologists, counsellors and some GPs. There are several different psychological therapies, but the two most commonly used in treating depression are cognitive behavioural therapy (CBT) and interpersonal theory (IPT).

Cognitive Behavioural Therapy (CBT)
CBT is based on the concept that the negative or distorted patterns of thought which are common in conditions like depression and anxiety can in turn affect mood and coping. It is not about simply thinking positively but rather aims to teach people to identify negative thoughts and replace them with more realistic ones (8).

Common types of negative or distorted thinking include all or nothing thinking (if something is not perfect then it is a complete failure); ignoring positives over the negatives (the ‘glass is half empty’ notion); catastrophising (exaggerating things so they become more serious than they really are) and personalisation (seeing oneself as the cause of negative events that are not really ones fault) (9).

CBT usually consists of a series of sessions taking place over a number of weeks. It may be conducted individually or in a group situation. CBT requires a certain level of commitment in both time and energy/motivation. For a person suffering from moderate to severe depression this can be an issue. This is why medication is sometimes prescribed in combination with psychological therapies as the medication will help the person feel well enough to attend sessions.

Interpersonal therapy (IPT)
IPT uses elements of CBT but is predominantly focused on current relationships. The therapy gets people to examine how they relate to and interact with important people in their lives. IPT is useful in situations where relationship breakdown/conflict or the loss of a loved one are significant contributing factors to a person’s depression.

Medication
The medications predominantly used in treating depression are antidepressants. Antidepressants work by changing levels of certain brain chemicals in the brain (eg., serotonin). Antidepressants can take several weeks to one to two months to work fully. For some people, the first antidepressant prescribed may not be suitable and they will have to try another. Antidepressants are not physically addictive.

The most commonly prescribed antidepressants are selective serotonin reuptake inhibitors (SSRIs). The advantage of SSRIs are that they generally have fewer side effects than older types of antidepressants (ie., tricyclic antidepressants). Side effects can include nausea, diarrhoea, sleep disturbance, headache, dizziness and reduced libido. The side effects experienced generally subside after a short time. Other antidepressants used include serotonin and norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants and monoamine oxidase inhibitors.

People need to continue taking antidepressants for a length of time following an improvement in their symptoms. This is often referred to as maintenance therapy. It is very important that people do not stop their medication prematurely (even if they feel well) as this can cause a relapse of the depression as well as unpleasant side effects. All decisions around stopping the medication or changing the dose should be made in conjunction with one’s GP or psychiatrist. The most common reason people stop taking their medication is because of unwanted side effects. If a person is concerned about side effects they should discuss this with their GP or psychiatrist. There may be ways that side effects can be minimised or better managed. Some people may need to take antidepressants on an ongoing basis (in the same way that a person with high blood pressure needs to take medication).

Electroconvulsive therapy (ECT)
ECT can play a role in treating severe depression that has not responded to other forms of treatment. It has been recognised as a highly effective form of treatment which often brings quick results. People’s beliefs about ECT are based on past practices. Today, ECT is administered under the direct supervision of a psychiatrist and with a patient under general anaesthetic. It consists of a brief, mild electric shock via electrodes placed on the head. A series of treatments are usually given over a number of weeks. The main side effect is memory impairment, but this is generally only mild and temporary.

Self-help
There are a number of strategies that people can practise themselves which may assist with depression. However, it is important that people do not solely rely on self-help methods if they are suffering from moderate to severe depression. Similarly, those with mild depression should seek professional help if their symptoms do not improve with self-help strategies.

Exercise
It is thought that exercise alters the levels of the brain chemical serotonin, resulting in an improved mood and sense of well-being. Other benefits of exercise include decreased isolation (particularly in team sport situations), reduced stress and a distraction from negative thinking (10). However, when a person is depressed they may not feel motivated enough to exercise. Enlisting friends to exercise with or participating in a planned activity (eg., weekly team sports fixture) can help keep exercise a regular activity.

Books and internet-based programs
There is some evidence that following a structured program from specific self-help books (referred to as bibliography) can help people with mild to moderate depression. These books are based on cognitive behavioural therapy (see Psychological therapies). The disadvantage of the books is that they may not be suitable for those with low reading level abilities and they require a certain amount of motivation. The two most popular books are Feeling Good by David Burns and Beating the Blues by Susan Tanner and Jillian Ball.

There are now also internet-based programs that provide a cognitive behavioural therapy approach. While these programs are relatively new, there is some evidence to suggest they are effective in treating those with depressive symptoms (11). An Australian example of an internet-based program is MoodGYM (see Other contacts).

Reducing alcohol and drug use
Many depression sufferers use alcohol and/or drugs (eg., cannabis) as a way of dealing with their depression. While such substances might make people feel better temporarily, in the long term they tend to cause additional problems. Those with depression who believe they may also have a substance misuse problem should discuss this with their GP.

Complementary therapies
There are a number of complementary therapies used in the treatment of depression. While the scientific evidence supporting the effectiveness of some is good, for others it is very limited. It is important that anyone using complementary therapies informs their doctor as therapies can interfere with conventional treatments. As with self-help strategies, complementary therapies should not be solely relied on by those with moderate to severe depression. Those with mild depression should seek professional help if their symptoms do not improve with complementary therapies.

One of the most popular complementary therapies used for depression is the herbal remedy St. John’s wort (Hypericum perforatum). While a review of its use in treating depression found the current scientific evidence is “inconsistent and confusing”, researchers concluded there were “benefits of hypericum in patients with mild to moderate depressive symptoms” (12). However, it appears to be of only minor benefit to those with severe or chronic depression. Side effects of St. John’s wort can include dry mouth, dizziness, constipation, gastrointestinal symptoms and an increased sensitivity to the sun (13). Most importantly, St. John’s wort interacts with a large number of medications including warfarin (blood thinning drug), anticonvulsants, oral contraceptives and antidepressants. For this reason it is vital that people always inform their doctor they are taking it.

Other complementary therapies for which there is some evidence include the amino acid S-adenosyl methionine (SAMe), folate supplementation, acupuncture, light therapy, massage, relaxation therapy, air ionisation (electrical devices which increase negative ions in the air) and yoga (14). Other therapies used in the treatment of depression include the herbs ginkgo biloba, vervain and lemon balm, homeopathy, natural progesterone, aromatherapy, music therapy, pet therapy and the supplementation of selenium, tyrosine, glutamine, Vitamin B, C, D and E. There is currently no evidence to support these treatments for depression (15).

References

1 beyondblue. What is Depression? http://www.beyondblue.org.au/index.aspx?link_id=1.3 [website] date accessed: 3 June 2004
2 Hickie I, Davenport T & Scott E. Depression: Out of the Shadows: A Guide To Understanding Depression and Its Treatment. Sydney: Australian Women's Weekly Health Series 2003 p66
3 Commonwealth Department of Health and Aged Care and Australian Institute of
Health and Welfare. National Health Priority Areas Report: Mental Health 1998 Canberra: AIHW 1999 p42
4 Hickie I, Davenport T & Scott E. Ibid p25
5 Hickie I, Davenport T & Scott E. Ibid p20-24
6 Commonwealth Department of Health and Aged Care and Australian Institute of Health and Welfare. National Health Priority Areas Report: Mental Health 1998 Canberra: AIHW 1999 p40
7 beyondblue. What is Depression? Ibid
8 Hickie I, Davenport T & Scott E. Ibid p53
9 Braiker, H b. Getting Up When You're Feeling Down: A Woman's Guide to Overcoming and Preventing Depression Lincoln, NE: IUniverse 2001 p157
10 Better Health Channel. Depression and exercise http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Depression_and
_exercise?OpenDocument [website] date accessed: 1 June 2004
11 Spek V et al. Internet-based cognitive behaviour therapy for symptoms of depression and anxiety: meta-analysis Psychological Medicine 2007; 37:3:319-28
12 Linde, K & Mulrow C D. St. John's wort for depression (Cochrane Review). In: The Cochrane Library, Issue 2 2004. Chichester, UK: John Wiley& Sons, Ltd.
13
Mischoulon D. Update and critique of natural remedies as antidepressant treatments Psychiatric Clin N Am 2007; 30:1:51-68
14 Form A F et al. Effectiveness of complementary and self-help treatments for depression MJA 2002:176;Sup 20:S84-96
15 Form A F et al

Further help and information from Women's Health Queensland Wide

Health Information Line:
Our free statewide line is staffed by women's health nurses and midwives. They provide women with up to date information, support and referral to health practitioners and services. Women can contact the Health Information Line by phone or email via the 'Ask a Health Question' page on the website. All phone calls and emails are confidential.
(07) 3839 9988 or 1800 017 676 (toll free outside Brisbane)

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Our free lending library offers a select range of books on major women's health topics. Topic-based booklists are availableon our website, or can be posted out; books can be requested by phone or email and are posted to borrowers.
Contact on administration : (07) 3839 9962

Website:
All our factsheets and booklets are available on our website. The website also features articles on women's health from our newsletter, student factsheets, upcoming events, library services and 'Ask a Health Question' page. A list of reputable links is also available where women can search for further information on health topics.
www.womhealth.org.au

Further reading

See our

Other Contacts/information sources

beyondblue
www.beyondblue.org.au
beyondblue is a national, independent, not-for-profit organisation working to address issues associated with depression, anxiety and related substance misuse disorders in Australia.

Black Dog Institute
www.blackdoginstitute.org.au
This website has been established by the Black Dog Institute attached to the Prince of Wales Hospital and affiliated with the University of NSW.

BluePages
bluepages.anu.edu.au
This website has been established by the Centre for Mental Health Research, The Australian National University.

Dark Side of the Mood
http://www.abc.net.au/health/library/stories/2007/06/05/1944066.htm
A feature of the ABC’s website, the section provides information on what is depression, what causes it and the different forms of treatment.

depressioNet
www.depressionet.com.au
depressioNet provides a comprehensive online resource for Australians living with depression and their families and friends.

Mental Health Carers Arafmi Australia
www.arafmiaustralia.asn.au/
An Australian agency which provides support for the families, carers and friends of those with mental health issues.

MoodGYM
www.moodgym.anu.edu.au/
A free, online cognitive behaviour therapy program for preventing depression, developed by a team of researchers at the Centre for Mental Health Research, Australian National University.

This factsheet was originally published by Women's Health Queensland Wide (Women's Health) in June 2000. It was revised by Kirsten Braun and the Editorial Committee at Women's Health in September 2004 and October 2007.

Last Modified:October 30, 2007

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